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The integrated code consists of 61 differential equations that are solved in Matlab

CagA modulates host cell iron homeostasis and fundamental metabolic functions of the bacterial cell, promoting the synthesis of polyunsaturated ether phospholipids (PUFA-ePLs) through increased expression of alkylglycerone phosphate synthase and 1-acylglycerol-3-phosphate O-acyltransferase 3, resulting in susceptibility to ferroptosis in GC cells [49]

Oralrespiratory axis Although oral microorganisms can also influence respiratory health through systemic routesincluding LPS dissemination, outer membrane vesicles, and pro-inflammatory cytokines entering the circulationthe defining feature of the oralrespiratory axis is the direct physical translocation of oral microbiota into the lower airways via microaspiration 192

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